The reports did not attribute blame for the apparent strikes, but internal groups fighting the Syrian government have no known capability to launch missiles from the sea.
Al-Ikhbariya said all two of the injured were hospitalized and the rest were released after treatment.
Head of the Syrian Observatory for Human Rights Rami Abdel Rahman told AFP that "violent explosions were caused by missiles targeting ammunition depots in the technical industries institute".
Around the time the plane disappeared, the Syrian coastal city of Latakia - near the Russian airbase to which the Il-20 was returning - came under attack from "enemy missiles", and missile defence batteries responded, Syrian state media reported.
The port city of Latakia is home to the family of Syrian President Bashar al-Assad, and a bastion of loyalty to his regime.
A Russian military aircraft with 14 people on board vanished from radar over the Mediterranean Sea, as Israeli warplanes attacked Syrian positions, Russia's defence ministry said.
Syrian state media on September 4 said its air defenses had downed several Israeli missiles in the coastal province of Tartus and in central Hama.
Syrian media has stated that a "number of missiles" have been shot down by its air defence network.
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From this point, it seemed a question of how many more the seven-time champions would add, but some gilt-edged chances were missed.
"The tracking of the Il-20 on flight control radars disappeared during an attack by four Israeli F-16 jets on Syrian facilities in Latakia Province", it said.
Russian Federation has issued conflicting reports about the source of the missile attack.
This month, Israel acknowledged having carried out more than 200 strikes in war-ravaged Syria over the past 18 months, mainly against Iranian targets.
The Israeli military refused to comment on claims they were behind the attack on Syria.
Hotlines are in place for those countries to share operational information on their deployments, but diplomats and military planners say there is still a high risk of one state inadvertently striking another country's forces.
Israel rarely acknowledges carrying out specific airstrikes in Syria, but is believed to be behind dozens of attacks on Iranian forces and Hezbollah weapons shipments.
Russian Federation has generally turned a blind eye to Israeli attacks on Iranian forces in Syria and the two countries' militaries maintain a hotline to avoid mistakes.