She fought back to beat Italian Camila Giorgi 3-6 6-3 6-4 in a fiercely contested quarter-final on Tuesday. She won her first WTA title in 2010 and followed that up by winning the prestigious Stuttgart tournament the next year.
But the 23-time major victor is heavily favoured to end her wait this week, fuelled by the thought of suffering the painful sting left by her rare defeats.
"It's important for me to have the losses".
"I'm going to go out there and just do what I can, do my best, see what happens".
Williams is playing only her fourth tournament since becoming a mother for the first time. While we may be a long way off an all-German final, there is every reason to applaud Goerges route to the semi-final.
But I think she's doing well.
"I'm always striving for perfection".
"It's different now obviously because I have the baby".
"Wow, it's pretty incredible", Goerges said. "I don't want her to have that".
"Here is some good news. We just need a good story".
Wimbledon 2018: Isner beats Raonic in quarter-final slug-fest
But Anderson has little time to rest his aching body before facing Novak Djokovic or Rafael Nadal in Sunday's final. As it became clear that Isner was due for another endless fifth set, tennis fans were far from delighted.
For the first time in the tournament, the 36-year-old was seriously challenged as unseeded Giorgi, playing in her first Grand Slam quarter-final, fought fire with fire to claim the opening set on Centre Court.
Serena Williams came up with a comeback to reach the semifinals at Wimbledon, then walked off Centre Court with her right index finger aloft.
Incredibly, Goerges had won only five matches in 10 previous visits to The All England Club - and none in the past five years - before arriving last week.
Kerber, the former No. 1 and two-time major champion who was the runner-up at Wimbledon two years ago, took advantage of Kasatkina's erratic serving and many errors to return to the last four. Everything from that point on seemed to click for Williams.
"It is a great opportunity to play Serena here where she has won so many times and is a great champion".
"I was maybe the better player in the first set but didn't actually take the chances I would have loved to take, but still found a way to somehow come back and close out that match". And she wouldn't mind renewing her rivalry with Kerber, whom she faced in two Grand Slam finals in 2016 - losing at the Australian Open before avenging that result at Wimbledon.
The action has continued from the Wimbledon quarter-finals with Germany's Julia Goerges beating a close friend to make the first semi-final of her career, while Juan Martin del Potro resumed his rain-interrupted match to set up a showdown with Rafael Nadal.
"This is tennis. Nobody is walking on the court saying OK, I'll give you a free match". I was just trying to stay focused on my serve. "It's so much fun".
In contrast, Goerges is in the Wimbledon semi-finals for the first time. She hasn't had to try very hard to win her points against an error-prone Ostapenko.